The TSN Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, and Hamster antigen. The TSN Antibody (Center) has been validated for the following applications: ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
This gene encodes a DNA-binding protein which specifically
recognizes conserved target sequences at the breakpoint junction of
chromosomal translocations. Translin polypeptides form a multimeric
structure that is responsible for its DNA-binding activity.
Recombination-associated motifs and translin-binding sites are
present at recombination hotspots and may serve as indicators of
breakpoints in genes which are fused by translocations. These
binding activities may play a crucial role in chromosomal
translocation in lymphoid neoplasms